All longevity research peptides

A synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal polypeptide epithalamin, studied for its effects on telomerase activity, circadian regulation, and lifespan extension in animal models.

A naturally occurring copper-binding tripeptide (Gly-His-Lys) that declines with age and is studied for tissue remodelling, anti-inflammatory gene-expression effects and skin/connective-tissue repair.

A 24-amino-acid mitochondrially-derived peptide encoded within the 16S rRNA gene, studied for cytoprotective, metabolic and neuroprotective signalling that declines with age.

A 16-amino-acid mitochondrially-derived peptide encoded within the mitochondrial 12S rRNA gene; functions as an exercise-mimetic regulator of insulin sensitivity, AMPK signalling and metabolic homeostasis.

A short synthetic tripeptide (Glu-Asp-Arg, EDR) from the Khavinson cytomedine family, studied for neuroprotective effects, oxidative-stress resistance and cognitive-function preservation in aged animals.

A mitochondrially-targeted aromatic-cationic tetrapeptide that binds inner-mitochondrial-membrane cardiolipin and stabilises mitochondrial cristae structure, studied in cardiac, renal and skeletal-muscle ageing.

Peptides and peptide-conjugate strategies investigated for their effects on cellular NAD⁺ levels, sirtuin activity and mitochondrial energy metabolism — including direct sirtuin-activating peptides and NMN/NR delivery analogues.

A 28-amino-acid synthetic equivalent of an N-acetylated peptide fragment originally isolated from thymic tissue, studied for immune-modulatory activity and increasingly examined in the context of immunosenescence and longevity.

A 29-amino-acid analogue of the active N-terminal fragment of growth hormone–releasing hormone (GHRH), studied as a pulsatile, physiological stimulator of pituitary GH secretion in the context of age-related GH decline.

A widely-studied research combination pairing a long-acting GHRH analogue (CJC-1295) with a selective ghrelin/GHS-R agonist (Ipamorelin) to produce synergistic, feedback-preserved pulsatile GH release.

A 15-amino-acid synthetic peptide fragment derived from a protective protein found in human gastric juice, studied for over three decades in animal models of tendon, ligament, gut and vascular repair.

A research designation commonly applied to synthetic fragments of Thymosin Beta-4, the body's most abundant actin-sequestering peptide, studied for its role in cell migration, angiogenesis and tissue-repair signalling.

A nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) isolated from rabbit cerebral venous blood in 1977 and named for its association with delta-wave EEG activity, studied for sleep architecture, stress-axis modulation and chronobiology.

A polypeptide complex extracted from calf thymus, developed in parallel with Epitalon by Vladimir Khavinson's St Petersburg group, studied as an immunomodulator addressing thymic involution and age-related immune decline.

A stabilised 44-amino-acid analogue of full-length growth hormone–releasing hormone (GHRH), FDA-approved since 2010 for HIV-associated lipodystrophy and the only GHRH analogue to hold a formal licence in a major regulatory market.

A synthetic heptapeptide analogue of the ACTH(4-10) fragment, developed in Russia as a non-hormonal neurotropic peptide and registered there for stroke rehabilitation and cognitive disorders, typically administered intranasally.

A synthetic heptapeptide analogue of the immunomodulatory peptide tuftsin, developed in Russia as a non-benzodiazepine anxiolytic and registered there for anxiety and adaptive-stress disorders, typically administered intranasally.

A designed D-retro-inverso peptide that disrupts the FOXO4-p53 interaction inside senescent cells, selectively triggering p53-driven apoptosis in senescent cells while sparing healthy tissue.